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PANTHERx Specialty Now Dispenses
JYNARQUE® (tolvaptan)

The first-and-only FDA-approved treatment to slow kidney function decline in adults who are at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).

To learn more about JYNARQUE® visit

  • Getting started on JYNARQUE®
    The FDA has mandated a Risk Evaluation and Mitigation Strategy (REMS) Program for JYNARQUE in ADPKD with the following components:

    • Medication Guide
    • Communication Plan
    • Elements to Assure Safe Use (ETASU)

    Each prospective prescriber must become certified to prescribe by agreeing to the REMS conditions, submitting a Prescriber Enrollment Form and passing an initial physician knowledge assessment.

    All patients treated with JYNARQUE will enroll in the JYNARQUE REMS Program via the Patient Prescriber Agreement Form.

    For more information on the JYNARQUE REMS Program or to access the prescriber and patient enrollment forms, visit

    To begin treatment with JYNARQUE, download the JYNARQUE Prescription Referral and Patient Consent Form

  • MyPASS Program For JYNARQUE®
    My Personalized ADPKD Support Services is a patient centric support program dedicated to helping people with autosomal dominant polycystic kidney disease (ADPKD) through their treatment journey. PANTHERx is a national REMS certified Specialty Pharmacy and is part of the MyPASS program. We provide a team of Nurse Case Managers who will assist you with the following:
  • Commercial copay savings
  • Help getting your medication on time
  • No-cost medication if there are delays with your insurance coverage
  • Help with your prescription
  • Information about how to take your medicine
  • Patient adherence and counseling
  • Prior authorization assistance and support
  • Assistance with JYNARQUE® REMS program enrollment
  • Important Contact Information
    Contact our team of dedicated nurse Case Managers
    Phone: (833) 599-2245       Fax: (412) 420-6242
    Fill in your contact information below and your personalized JYNARQUE Case Manager will be contact with you within one business day
  • Why Panther Specialty Pharmacy?
    PANTHERx® Specialty Pharmacy is proud to partner with Otsuka to help provide award winning customer service to our JYNARQUE patients. PANTHERx® Specialty Pharmacy, THE Rare Disease Specialty Pharmacy®, is a national, quad-accredited, market leader in patient satisfaction, specialty pharmacy headquartered in Pittsburgh, Pennsylvania.

Drug Overview

Drug Name


Generic Name




FDA Indication

Autosomal Dominant Polycystic Kidney Disease

Dosage Forms/ Strengths

JYNARQUE 45mg/15mg (oral tablets)
JYNARQUE 60mg/30mg (oral tablets)
JYNARQUE 90mg/30mg (oral tablets)

Program Websites:

PANTHERx Specialty
Jynarque Case
Management Support:
(833) 599-2245